Welcome to the fascinating world of Molecular Biology and Genetics — a cornerstone of biotechnology and a field that unravels the intricate mechanisms of life at its most fundamental level. This book is designed to provide first-year biotechnology students with a comprehensive introduction to these two interconnected fields which are the heart of modern life sciences, offering insights into the molecular blueprint of life and the mechanisms by which it is inherited, expressed, and modified. Understanding molecular biology and genetics is crucial for anyone aspiring to innovate in biotechnology, medicine, agriculture, or environmental science. Molecular biology, laying a strong foundation for their academic journey and future scientific endeavours.
The field of molecular biology has undergone a remarkable transformation over the last few decades, driven by revolutionary discoveries such as the structure of DNA, the Human Genome Project, Vaccine by Genetic Engineering. These break throughs have not only deepened our understanding of life but also paved the way for transformative applications in medicine, agriculture, and environmental science with Genetics. It provides a clear, systematic, and accessible introduction to molecular biology and genetics, ensuring a strong conceptual foundation.
To enhance the learning experience, we have included visual aids such as diagrams, tables, and flowcharts to simplify complex processes.
Recognizing the diverse backgrounds of first-year students of Mumbai University with NEP 2020, this book includes helpful features such as diagrams, simplified explanations, and end-of-chapter summaries, review questions, are provided to reinforce understanding and encourage critical thinking. The chapters are arranged to gradually build your understanding, beginning with the structure and function of nucleic acids, moving to gene interaction and modified mendelian ratio and Replication in next Module.
Contents –
Module 1: Nucleic Acid, and Genetics
1. Composition and Structure of DNA and RNA
2. Organisation of Prokaryotic and Eukaryotic Chromosomes
3. Extensions of Deviations from Mendelian Genetic Principles
4. Gene Interactions and Modified Mendelian Ratios
5. Mendelian Genetics in Humans
Module 2: Replication of DNA
6. Models of DNA Replication
7. DNA Replication in Eukaryotes
8. Enzymes and Proteins Involved in DNA Replication